Expert Asthma & Pulmonary Care with Dr. Frank Hull, MD
Dr. Frank Hull
Phone: 954-522-7226
Research: 954-520-7296
Fax: 954-388-2222

Breathe Easier with Targeted Biologic Therapies

Beyond inhalers: Precision treatments for stubborn asthma available right here in Plantation, Florida.

Traditional asthma medications often treat all asthma the same way. Biologic therapies take a different approach—targeting specific molecules in the inflammatory cascade that drives YOUR asthma.

What Are Biologics?

Biologic therapies are advanced treatments, often antibodies, made using biotechnology. Unlike conventional medications (like inhaled steroids) that broadly suppress inflammation, biologics precisely target specific parts of the immune system involved in asthma, such as specific interleukins (IL-4, IL-5, IL-13), alarmins (TSLP), or antibodies (IgE).

Benefits of biologic therapy can include:

  • Fewer asthma attacks (exacerbations)
  • Reduced need for oral steroids (like prednisone)
  • Better day-to-day symptom control
  • Improved lung function
  • Enhanced quality of life

FDA-Approved Biologics at Our Clinic

We offer access to the full range of FDA-approved biologics, matching the therapy to your specific asthma type:

Anti-IgE Therapy (e.g., Omalizumab/Xolair)

  • How it works: Blocks IgE antibodies that trigger allergic asthma responses.
  • Ideal for: Patients with moderate to severe allergic asthma and elevated IgE levels.
  • Administration: Injection every 2-4 weeks.
  • Results: Can significantly reduce asthma attacks triggered by allergens.

Anti-IL-5 / Anti-IL-5 Receptor Therapies (e.g., Mepolizumab/Nucala, Reslizumab/Cinqair, Benralizumab/Fasenra)

  • How they work: Target interleukin-5 (IL-5) or its receptor to reduce eosinophil-driven inflammation.
  • Ideal for: Patients with severe eosinophilic asthma (high blood eosinophil counts).
  • Administration: Injection every 4-8 weeks (depending on the specific drug).
  • Results: Highly effective at reducing exacerbations and eosinophil counts in eligible patients.

Anti-IL-4 / IL-13 Therapy (e.g., Dupilumab/Dupixent)

  • How it works: Blocks the receptor for two key inflammatory molecules (IL-4 and IL-13) simultaneously.
  • Ideal for: Patients with eosinophilic or allergic asthma, especially those with related conditions like atopic dermatitis or chronic rhinosinusitis with nasal polyps. Also approved for certain COPD patients.
  • Administration: Injection every 2 weeks.
  • Results: Significant improvement in lung function, exacerbation reduction, and quality of life.

Anti-TSLP Therapy (e.g., Tezepelumab/Tezspire)

  • How it works: Blocks Thymic Stromal Lymphopoietin (TSLP), an early "alarmin" trigger high up in the inflammatory cascade.
  • Ideal for: A broad range of severe asthma patients, including those with lower eosinophil counts or non-allergic triggers.
  • Administration: Injection every 4 weeks.
  • Results: Proven to reduce exacerbations across different asthma types by targeting inflammation at a very early stage.

Research Biologics: Tomorrow's Treatments Today

Our clinic actively participates in clinical trials investigating cutting-edge biologic therapies not yet widely available, including treatments targeting IL-33, IL-17, BTK inhibitors, and other novel pathways.

Don't wait for these treatments to become widely available. Access them now through our research program in Plantation, FL.

See If You Qualify for Biologic Therapy Learn About Our Clinical Trials